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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK6 All Species: 21.82
Human Site: T60 Identified Species: 34.29
UniProt: Q9NQU5 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQU5 NP_001122100.1 681 74869 T60 V V D P S R I T R V Q L Q P M
Chimpanzee Pan troglodytes XP_510301 627 67581 P39 P W P E P Q S P R V L P N G L
Rhesus Macaque Macaca mulatta XP_001093484 681 74821 T60 V V D P S R I T R V Q L Q P M
Dog Lupus familis XP_544614 968 105825 T347 V V D P S R I T R V Q L Q P M
Cat Felis silvestris
Mouse Mus musculus Q3ULB5 682 74848 R61 V D P S R I T R V Q L Q P M K
Rat Rattus norvegicus Q62829 544 60692
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515215 639 68748 K51 L D T L R R P K P V V D P S R
Chicken Gallus gallus XP_426393 667 74767 T60 V V D P S R I T R M Q L Q P M
Frog Xenopus laevis NP_001082100 650 73749 D55 K R P K P L V D P S Y I T T I
Zebra Danio Brachydanio rerio XP_001919719 693 77347 T60 M V D P S R I T P V E L K P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S51 G N N Q I L K S S N R P L P L
Honey Bee Apis mellifera XP_001122147 624 70155 P36 E G K F V G L P L Q W A S I V
Nematode Worm Caenorhab. elegans Q17850 572 63863
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 S211 P V S T P V I S K P S M T T T
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 S209 S A A P A P T S T T T I A H S
Conservation
Percent
Protein Identity: 100 52.7 98.5 66.4 N.A. 92.5 30.6 N.A. 62.2 75.9 46.7 52.5 N.A. 44.3 44.9 29.8 N.A.
Protein Similarity: 100 60.7 98.9 67.6 N.A. 95.5 48.4 N.A. 69.9 82.3 61.6 64.5 N.A. 57.5 57.5 47.2 N.A.
P-Site Identity: 100 13.3 100 100 N.A. 6.6 0 N.A. 13.3 93.3 0 66.6 N.A. 6.6 0 0 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 6.6 0 N.A. 20 100 20 86.6 N.A. 33.3 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.5 28
Protein Similarity: N.A. N.A. N.A. N.A. 43.1 41.6
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 7 0 0 0 0 0 0 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 34 0 0 0 0 7 0 0 0 7 0 0 0 % D
% Glu: 7 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 7 0 0 0 7 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 7 7 40 0 0 0 0 14 0 7 7 % I
% Lys: 7 0 7 7 0 0 7 7 7 0 0 0 7 0 14 % K
% Leu: 7 0 0 7 0 14 7 0 7 0 14 34 7 0 14 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 7 0 7 27 % M
% Asn: 0 7 7 0 0 0 0 0 0 7 0 0 7 0 0 % N
% Pro: 14 0 20 40 20 7 7 14 20 7 0 14 14 40 0 % P
% Gln: 0 0 0 7 0 7 0 0 0 14 27 7 27 0 0 % Q
% Arg: 0 7 0 0 14 40 0 7 34 0 7 0 0 0 7 % R
% Ser: 7 0 7 7 34 0 7 20 7 7 7 0 7 7 7 % S
% Thr: 0 0 7 7 0 0 14 34 7 7 7 0 14 14 7 % T
% Val: 34 40 0 0 7 7 7 0 7 40 7 0 0 0 7 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _